Greenville has become one of the South's quiet success stories, with a revitalized downtown that has helped grow a lively local arts scene. In the Upstate of South Carolina, its open mics welcome comedians, musicians, poets, and storytellers into walkable bars, coffee shops, and performance spaces, where supportive crowds make experimentation easy. The scene is friendly and steadily expanding, offering a comfortable place to find your voice or test new material. A strong sense of local pride keeps audiences turning out. This regularly updated list gathers the latest details on sign-ups, costs, times, and venues to help you find the best open mics in Greenville.

Greenville

South Carolina

United States of America

All Venues in Greenville

South Carolina Governor's School for the Arts and Humanities

Swanson's Warehouse

The Comedy Zone

THE Pub for What Ales You

The Radio Room